You can always try opening the remore and adjusting the pads. Usually they have a conductive coating that you can remove or protect with a piece of tape. Alternatively, other remotes may be synced to the device. There are two types of remotes, RF and Infrered. The INfrared must be pointed at the devide whereas the RF works from nearby rooms, etc.
I ahve a car remote with a PANIC button on the back. I opened the remote and glued the rubber button in place so it would not press.
On a Roku TV and perhaps other Roku devices, you can use your smart phone and a Roku app to control TVs and Roku devices. It does not have those ‘pesky’ ad supported buttons.